Bonifay is a city in Holmes County, Florida, United States. Bonifay was given its name from a prominent family that had a brickmaking factory in Pensacola. Frank Bonifay, the man behind the town's name, bought a stake in the Louisville and Nashville Railroad, now CSX. As W. D. Chipley connected the rural Florida Panhandle, along the way he came up with names for certain communities the railroad bisected.As of the 2010 census the population was 2,798. It is the county seat of Holmes County.